A novel myelin P0–specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy

Autoimmune-prone nonobese diabetic mice deficient for B7-2 spontaneously develop an autoimmune peripheral neuropathy mediated by inflammatory CD4(+) T cells that is reminiscent of Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy. To determine the etiology of this disease...

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Autores principales: Louvet, Cédric, Kabre, Beniwende G., Davini, Dan W., Martinier, Nicolas, Su, Maureen A., DeVoss, Jason J., Rosenthal, Wendy L., Anderson, Mark S., Bour-Jordan, Hélène, Bluestone, Jeffrey A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699118/
https://ncbi.nlm.nih.gov/pubmed/19221395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082113
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