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T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
After homing to lymph nodes, CD8(+) T cells are primed by dendritic cells (DCs) in three phases. During phase one, T cells undergo brief serial contacts with DCs for several hours, whereas phase two is characterized by stable T cell–DC interactions. We show here that the duration of phase one and T...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698867/ https://ncbi.nlm.nih.gov/pubmed/18204450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1559 |
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