Regulation of H3K4 Trimethylation via Cps40 (Spp1) of COMPASS Is Monoubiquitination Independent: Implication for a Phe/Tyr Switch by the Catalytic Domain of Set1

The multiprotein complex Set1/COMPASS is the founding member of the histone H3 lysine 4 (H3K4) methyltransferases, whose human homologs include the MLL and hSet1 complexes. COMPASS can mono-, di-, and trimethylate H3K4, but transitioning to di- and trimethylation requires prior H2B monoubiquitinatio...

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Bibliografiske detaljer
Main Authors: Takahashi, Yoh Hei, Lee, Jung Shin, Swanson, Selene K., Saraf, Anita, Florens, Laurence, Washburn, Michael P., Trievel, Raymond C., Shilatifard, Ali
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698764/
https://ncbi.nlm.nih.gov/pubmed/19398585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00013-09
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