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Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity
Polyubiquitination can mediate several different biochemical functions, determined in part by which lysine of ubiquitin is used to link the polyubiquitin chain. Among the HECT domain ubiquitin ligases, some, such as human E6AP, preferentially catalyze the formation of K48-linked polyubiquitin chains...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698738/ https://ncbi.nlm.nih.gov/pubmed/19364824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00240-09 |
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