Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice

Calsequestrin-1 (CASQ1) is a moderate-affinity, high-capacity Ca(2+)-binding protein in the sarcoplasmic reticulum (SR) terminal cisternae of skeletal muscle. CASQ1 functions as both a Ca(2+)-binding protein and a luminal regulator of ryanodine receptor (RYR1)-mediated Ca(2+) release. Mice lacking s...

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Detalhes bibliográficos
Main Authors: Dainese, Marco, Quarta, Marco, Lyfenko, Alla D., Paolini, Cecilia, Canato, Marta, Reggiani, Carlo, Dirksen, Robert T., Protasi, Feliciano
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698659/
https://ncbi.nlm.nih.gov/pubmed/19237502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-121335
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