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Distinctive roles of different β-amyloid 42 aggregates in modulation of synaptic functions

To determine how endogenously secreted β-amyloid 42 (Aβ42) aggregates regulate synaptic functions, we examined effects of Aβ42 at the neuromuscular junction of Drosophila larvae. Voltage-clamp recordings of synaptic transmission and optical analysis of vesicle recycling at presynaptic terminals show...

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Main Authors: Chiang, Hsueh-Cheng, Iijima, Koichi, Hakker, Inessa, Zhong, Yi
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698658/
https://ncbi.nlm.nih.gov/pubmed/19255256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-121152
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