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The GABA(A) agonist muscimol attenuates induced airway constriction in guinea pigs in vivo

GABA(A) channels are ubiquitously expressed on neuronal cells and act via an inward chloride current to hyperpolarize the cell membrane of mature neurons. Expression and function of GABA(A) channels on airway smooth muscle cells has been demonstrated in vitro. Airway smooth muscle cell membrane hype...

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Библиографические подробности
Главные авторы: Gleason, Neil R., Gallos, George, Zhang, Yi, Emala, Charles W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698643/
https://ncbi.nlm.nih.gov/pubmed/19213928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.91314.2008
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