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The GABA(A) agonist muscimol attenuates induced airway constriction in guinea pigs in vivo

GABA(A) channels are ubiquitously expressed on neuronal cells and act via an inward chloride current to hyperpolarize the cell membrane of mature neurons. Expression and function of GABA(A) channels on airway smooth muscle cells has been demonstrated in vitro. Airway smooth muscle cell membrane hype...

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Hlavní autoři: Gleason, Neil R., Gallos, George, Zhang, Yi, Emala, Charles W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698643/
https://ncbi.nlm.nih.gov/pubmed/19213928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.91314.2008
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