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The GABA(A) agonist muscimol attenuates induced airway constriction in guinea pigs in vivo

GABA(A) channels are ubiquitously expressed on neuronal cells and act via an inward chloride current to hyperpolarize the cell membrane of mature neurons. Expression and function of GABA(A) channels on airway smooth muscle cells has been demonstrated in vitro. Airway smooth muscle cell membrane hype...

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Detalles Bibliográficos
Main Authors: Gleason, Neil R., Gallos, George, Zhang, Yi, Emala, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698643/
https://ncbi.nlm.nih.gov/pubmed/19213928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.91314.2008
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