Kinetic Dependence of Paramyxovirus Entry Inhibition

Peptides derived from conserved heptad repeat (HR) regions of paramyxovirus fusion (F) proteins inhibit viral fusion by interfering with the formation of the fusogenic six-helix bundle structure. Peptide efficacy is affected by the strength of the peptide association with the target virus's com...

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Bibliographic Details
Main Authors: Porotto, Matteo, Yokoyama, Christine C., Orefice, Gianmarco, Kim, Han-Sung, Aljofan, Mohamed, Mungall, Bruce A., Moscona, Anne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698554/
https://ncbi.nlm.nih.gov/pubmed/19369345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00416-09
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