Human Papillomavirus Type 16 (HPV-16) Virus-Like Particle L1-Specific CD8(+) Cytotoxic T Lymphocytes (CTLs) Are Equally Effective as E7-Specific CD8(+) CTLs in Killing Autologous HPV-16-Positive Tumor Cells in Cervical Cancer Patients: Implications for L1 Dendritic Cell-Based Therapeutic Vaccines

Papillomavirus-like particles (VLPs) based on L1 capsid protein represent a promising prophylactic vaccine against human papillomavirus (HPV) infections. However, cell-mediated immune responses against this antigen are believed to be of limited therapeutic value in established HPV-infected cervical...

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Main Authors: Bellone, Stefania, El-Sahwi, Karim, Cocco, Emiliano, Casagrande, Francesca, Cargnelutti, Marilisa, Palmieri, Michela, Bignotti, Eliana, Romani, Chiara, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698533/
https://ncbi.nlm.nih.gov/pubmed/19386711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02443-08
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