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Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14

A new cytochrome P450 monooxygenase, FcpC, from Streptomyces virginiae IBL-14 has been identified. This enzyme is found to be responsible for the bioconversion of a pyrano-spiro steroid (diosgenone) to a rare nuatigenin-type spiro steroid (isonuatigenone), which is a novel C-25-hydroxylated diosgeno...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Wang, Feng-Qing, Wei, Dong-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698366/
https://ncbi.nlm.nih.gov/pubmed/19376895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02606-08
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