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Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets

Overaccumulation of lipids in nonadipose tissues of obese rodents may lead to lipotoxic complications such as diabetes. To assess the pathogenic role of the lipogenic transcription factor, sterol regulatory element binding protein 1 (SREBP-1), we measured its mRNA in liver and islets of obese, lepti...

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Bibliographische Detailangaben
Hauptverfasser: Kakuma, Tetsuya, Lee, Young, Higa, Moritake, Wang, Zhuo-wei, Pan, Wentong, Shimomura, Iichiro, Unger, Roger H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26983/
https://ncbi.nlm.nih.gov/pubmed/10900012
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