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Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development

Pak1 (p21 activated kinase 1) is a serine/threonine kinase implicated in regulation of cell motility and survival and in malignant transformation of mammary epithelial cells. In addition, the dynein light chain, LC8, has been described to cooperate with Pak1 in malignant transformation of breast can...

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Autors principals: Lightcap, Christine M., Kari, Gabor, Arias-Romero, Luis E., Chernoff, Jonathan, Rodeck, Ulrich, Williams, John C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698211/
https://ncbi.nlm.nih.gov/pubmed/19557173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006025
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