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Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development

Pak1 (p21 activated kinase 1) is a serine/threonine kinase implicated in regulation of cell motility and survival and in malignant transformation of mammary epithelial cells. In addition, the dynein light chain, LC8, has been described to cooperate with Pak1 in malignant transformation of breast can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lightcap, Christine M., Kari, Gabor, Arias-Romero, Luis E., Chernoff, Jonathan, Rodeck, Ulrich, Williams, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698211/
https://ncbi.nlm.nih.gov/pubmed/19557173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006025
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