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Formal Synthesis of (−)-Kendomycin Featuring a Prins-Cyclization to Construct the Macrocycle
The kendomycin skeleton was prepared by a highly convergent strategy in which the benzofuran fragment and the acyclic iodide fragment were prepared by standard methods and joined using a Suzuki coupling. The distinctive reaction in our approach was an intramolecular Prins cyclization that assembles...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697922/ https://ncbi.nlm.nih.gov/pubmed/18767844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805187p |
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