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Formal Synthesis of (−)-Kendomycin Featuring a Prins-Cyclization to Construct the Macrocycle

The kendomycin skeleton was prepared by a highly convergent strategy in which the benzofuran fragment and the acyclic iodide fragment were prepared by standard methods and joined using a Suzuki coupling. The distinctive reaction in our approach was an intramolecular Prins cyclization that assembles...

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Detaylı Bibliyografya
Asıl Yazarlar: Bahnck, Kevin B., Rychnovsky, Scott D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697922/
https://ncbi.nlm.nih.gov/pubmed/18767844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805187p
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