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Do cell surface trafficking impairments account for variable cell surface sodium iodide symporter levels in breast cancer?
The Na(+)/I(-) symporter (NIS) is a transmembrane glycoprotein that mediates iodide uptake into thyroid follicular cells and serves as the molecular basis of radioiodine imaging and therapy for thyroid cancer patients. The finding that NIS protein is present in 80-90% of breast tumors suggests that...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697904/ https://ncbi.nlm.nih.gov/pubmed/18500672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0059-5 |
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