Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice

BACKGROUND AND PURPOSE: Reactive oxygen species (ROS) derived from Nox2-containing reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity is reportedly detrimental in cerebrovascular disease. However, ROS generation by other Nox isoforms may have a physiological role. N...

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Detalhes bibliográficos
Main Authors: Jackman, KA, Miller, AA, De Silva, TM, Crack, PJ, Drummond, GR, Sobey, CG
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697707/
https://ncbi.nlm.nih.gov/pubmed/19175604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00073.x
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