Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide

Cerebral infarct volume is typically smaller in premenopausal females than in age-matched males after ischemic stroke, but the underlying mechanisms are poorly understood. In this study we provide evidence in mice that this gender difference only occurs when the ischemic brain is reperfused. The lim...

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Detalhes bibliográficos
Main Authors: Brait, Vanessa H, Jackman, Katherine A, Walduck, Anna K, Selemidis, Stavros, Diep, Henry, Mast, Anja E, Guida, Elizabeth, Broughton, Brad RS, Drummond, Grant R, Sobey, Christopher G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949221/
https://ncbi.nlm.nih.gov/pubmed/20145655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.14
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