Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide

Cerebral infarct volume is typically smaller in premenopausal females than in age-matched males after ischemic stroke, but the underlying mechanisms are poorly understood. In this study we provide evidence in mice that this gender difference only occurs when the ischemic brain is reperfused. The lim...

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Bibliographic Details
Main Authors: Brait, Vanessa H, Jackman, Katherine A, Walduck, Anna K, Selemidis, Stavros, Diep, Henry, Mast, Anja E, Guida, Elizabeth, Broughton, Brad RS, Drummond, Grant R, Sobey, Christopher G
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949221/
https://ncbi.nlm.nih.gov/pubmed/20145655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.14
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