Loss of Cbl-b Increases Osteoclast Bone-Resorbing Activity and Induces Osteopenia

Cbl proteins are multifunctional adaptor molecules that modulate cellular activity by targeting the ubiquitylating system, endocytic complexes, and other effectors to a wide variety of regulatory proteins, especially activated receptor and nonreceptor tyrosine kinases. Cbl and Cbl-b perform unique f...

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Detalhes bibliográficos
Main Authors: Nakajima, Arata, Sanjay, Archana, Chiusaroli, Riccardo, Adapala, Naga Suresh, Neff, Lynn, Itzsteink, Cecile, Horne, William C., Baron, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697622/
https://ncbi.nlm.nih.gov/pubmed/19257814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.090205
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