Dynamin Forms a Src Kinase–sensitive Complex with Cbl and Regulates Podosomes and Osteoclast Activity

Podosomes are highly dynamic actin-containing adhesion structures found in osteoclasts, macrophages, and Rous sarcoma virus (RSV)-transformed fibroblasts. After integrin engagement, Pyk2 recruits Src and the adaptor protein Cbl, forming a molecular signaling complex that is critical for cell migrati...

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Detalhes bibliográficos
Main Authors: Bruzzaniti, Angela, Neff, Lynn, Sanjay, Archana, Horne, William C., De Camilli, Pietro, Baron, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165412/
https://ncbi.nlm.nih.gov/pubmed/15872089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1117
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