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Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum

The inner membrane of the nuclear envelope (NE) was previously shown to contain a Na/Ca exchanger (NCX) tightly linked to GM1 ganglioside that mediates transfer of nucleoplasmic Ca(2+) to the NE lumen and constitutes a cytoprotective mechanism. This transfer was initially observed with isolated nucl...

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Detalhes bibliográficos
Main Authors: Wu, Gusheng, Xie, Xin, Lu, Zi-Hua, Ledeen, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697114/
https://ncbi.nlm.nih.gov/pubmed/19541636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903408106
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