Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with α5β1 Integrin Initiates Neurite Outgrowth

Previous studies demonstrated that cross-linking of GM1 ganglioside with multivalent ligands, such as B subunit of cholera toxin (CtxB), induced Ca(2+) influx through an unidentified, voltage-independent channel in several cell types. Application of CtxB to undifferentiated NG108-15 cells resulted i...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Wu, Gusheng, Lu, Zi-Hua, Obukhov, Alexander G., Nowycky, Martha C., Ledeen, Robert W.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672619/
https://ncbi.nlm.nih.gov/pubmed/17626205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4266-06.2007
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