V(D)J recombination is not activated by demethylation of the kappa locus
V(D)J recombination is thought to be regulated by changes in the accessibility of target sites, such as modulation of methylation. To test whether demethylation of the kappa locus can activate recombination, we generated two recombinationally active B cell lines in which the gene for maintenance of...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.150218497 |
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