V(D)J recombination is not activated by demethylation of the kappa locus
V(D)J recombination is thought to be regulated by changes in the accessibility of target sites, such as modulation of methylation. To test whether demethylation of the kappa locus can activate recombination, we generated two recombinationally active B cell lines in which the gene for maintenance of...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.150218497 |
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