Regulator of G protein signaling proteins differentially modulate signaling of μ and δ opioid receptors

Effects of regulator of G protein signaling (RGS) proteins on μ and δ opioid receptors were investigated in HEK293 cells. Co-expression of RGS1, RGS2, RGS4, RGS9, RGS10 or RGS19 (Gα-interacting protein (GAIP)) significantly reduced [Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol]-Enkephalin (DAMGO)-induced inhib...

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Detalhes bibliográficos
Main Authors: Xie, Zhihua, Li, Zhisong, Guo, Lei, Ye, Caiying, Li, Juan, Yu, Xiaoli, Yang, Huifen, Wang, Yulin, Chen, Chongguang, Zhang, Dechang, Liu-Chen, Lee-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696627/
https://ncbi.nlm.nih.gov/pubmed/17433292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.03.005
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