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Subcellular Localization of μ-Opioid Receptor G(s) Signaling

In membranes obtained from μ-opioid receptor (MOR) expressing Chinese hamster ovary (CHO) cells (MOR-CHO), the MOR-selective agonist sufentanil produced a concentration-dependent stimulation of guanosine 5′-O-(3-[(35)S]thio)triphosphate binding to G(s)α that was abolished by blocking MOR with naloxo...

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Bibliografiske detaljer
Main Authors: Chakrabarti, Sumita, Chang, Andrew, Gintzler, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846030/
https://ncbi.nlm.nih.gov/pubmed/20097777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.165142
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