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A Novel Function for p53: Regulation of Growth Cone Motility through Interaction with Rho Kinase
The transcription factor p53 suppresses tumorgenesis by regulating cell proliferation and migration. We investigated whether p53 could also control cell motility in postmitotic neurons. p53 isoforms recognized by phospho-p53-specific (at Ser-15) or “mutant” conformation-specific antibodies were high...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696279/ https://ncbi.nlm.nih.gov/pubmed/19386914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0420-09.2009 |
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