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17-β-Estradiol increases neuronal excitability through MAP kinase-induced calpain activation
17-β-Estradiol (E2) is a steroid hormone involved in numerous brain functions. E2 regulates synaptic plasticity in part by enhancing NMDA receptor function and spine density in the hippocampus, resulting in increased long-term potentiation and facilitation of learning and memory. As the calcium-depe...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799831/ https://ncbi.nlm.nih.gov/pubmed/19995977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912558106 |
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