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C/EBPα:AP-1 Leucine Zipper Heterodimers Bind Novel DNA Elements, Activate the PU.1 Promoter, and Direct Monocyte Lineage Commitment More Potently Than C/EBPα Homodimers or AP-1

The basic-region leucine zipper (BR-LZ or bZIP) transcription factors dimerize via their LZ domains to position the adjacent BRs for DNA-binding. Members of the C/EBP, AP-1, and CREB/ATF bZIP subfamilies form homodimeric or heterodimeric complexes with other members of the same subset and bind speci...

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Autors principals: Cai, DH, Wang, D, Keefer, J, Yeamans, C, Hensley, K, Friedman, AD
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696120/
https://ncbi.nlm.nih.gov/pubmed/18026136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210940
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