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The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain.

The rat CYP2D5 P-450 gene is activated in the liver during postnatal development. We previously showed that liver-specific transcription of the CYP2D5 gene is dictated by a proximal promoter element, termed 2D5, that is composed of a binding site for Sp1 or a related factor, and an adjacent cryptic...

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Publicat a:Mol Cell Biol
Autors principals: Lee, Y H, Williams, S C, Baer, M, Sterneck, E, Gonzalez, F J, Johnson, P F
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232051/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2038
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