The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain.

The rat CYP2D5 P-450 gene is activated in the liver during postnatal development. We previously showed that liver-specific transcription of the CYP2D5 gene is dictated by a proximal promoter element, termed 2D5, that is composed of a binding site for Sp1 or a related factor, and an adjacent cryptic...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lee, Y H, Williams, S C, Baer, M, Sterneck, E, Gonzalez, F J, Johnson, P F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2038
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