Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

Ebola Zaire virus is highly pathogenic for humans, with case fatality rates approaching 90% in large outbreaks in Africa. The virus replicates in macrophages and dendritic cells (DCs), suppressing production of type I interferons (IFNs) while inducing the release of large quantities of proinflammato...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chang, Tsung-Hsien, Kubota, Toru, Matsuoka, Mayumi, Jones, Steven, Bradfute, Steven B., Bray, Mike, Ozato, Keiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696038/
https://ncbi.nlm.nih.gov/pubmed/19557165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000493
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares