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Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma
Constitutive activation of the insulin-like growth factor (IGF)-signaling axis is frequently observed in human hepatocellular carcinoma (HCC). Especially the overexpression of the fetal growth factor IGF-II, IGF-Ireceptor (IGF-IR), and cytoplasmic downstream effectors such as insulin-receptor substr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The WJG Press and Baishideng
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695909/ https://ncbi.nlm.nih.gov/pubmed/18350600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.1690 |
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