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Potentiating the Efficacy of Molecular Targeted Therapy for Hepatocellular Carcinoma by Inhibiting the Insulin-Like Growth Factor Pathway

Insulin-like growth factor (IGF) signaling pathway is an important regulatory mechanism of tumorigenesis and drug resistance in many cancers. The present study explored the potential synergistic effects between IGF receptor (IGFR) inhibition and other molecular targeted agents (MTA) in HCC cells. HC...

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Detalhes bibliográficos
Main Authors: Ou, Da-Liang, Lee, Bin-Shyun, Chang, Ya-Chi, Lin, Liang-In, Liou, Jun-Yang, Hsu, Chiun, Cheng, Ann-Lii
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688529/
https://ncbi.nlm.nih.gov/pubmed/23818948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066589
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