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Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo
AIM: To generate an adenoviral vector specifically targeting the EphA2 receptor (EphA2R) highly expressed on pancreatic cancer cells in vivo. METHODS: YSA, a small peptide ligand that binds the EphA2R with high affinity, was inserted into the HI loop of the adenovirus serotype 5 fiber knob. To furth...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The WJG Press and Baishideng
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695891/ https://ncbi.nlm.nih.gov/pubmed/19522026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.2754 |
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