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Gene Therapy for Progressive Familial Intrahepatic Cholestasis: Current Progress and Future Prospects

Progressive Familial Intrahepatic Cholestasis (PFIC) are inherited severe liver disorders presenting early in life, with high serum bile salt and bilirubin levels. Six types have been reported, two of these are caused by deficiency of an ABC transporter; ABCB11 (bile salt export pump) in type 2; ABC...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bosma, Piter J., Wits, Marius, Oude-Elferink, Ronald P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796371/
https://ncbi.nlm.nih.gov/pubmed/33383947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010273
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