An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension

Granins regulate secretory vesicle formation in neuroendocrine cells, and granin-derived peptides are co-released with neurotransmitters as modulatory signals at sympathetic sites. We report evidence for association between a regulatory polymorphism in Secretogranin II (SCG2) and hypertension in Afr...

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Detalhes bibliográficos
Main Authors: Wen, Gen, Wessel, Jennifer, Zhou, Weidong, Ehret, Georg B., Rao, Fangwen, Stridsberg, Mats, Mahata, Sushil K., Gent, Peter M., Das, Madhusudan, Cooper, Richard S., Chakravarti, Aravinda, Zhou, Huilin, Schork, Nicholas J., O’Connor, Daniel T., Hamilton, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695823/
https://ncbi.nlm.nih.gov/pubmed/17584765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddm123
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