An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension

Granins regulate secretory vesicle formation in neuroendocrine cells, and granin-derived peptides are co-released with neurotransmitters as modulatory signals at sympathetic sites. We report evidence for association between a regulatory polymorphism in Secretogranin II (SCG2) and hypertension in Afr...

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Xehetasun bibliografikoak
Egile Nagusiak: Wen, Gen, Wessel, Jennifer, Zhou, Weidong, Ehret, Georg B., Rao, Fangwen, Stridsberg, Mats, Mahata, Sushil K., Gent, Peter M., Das, Madhusudan, Cooper, Richard S., Chakravarti, Aravinda, Zhou, Huilin, Schork, Nicholas J., O’Connor, Daniel T., Hamilton, Bruce A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695823/
https://ncbi.nlm.nih.gov/pubmed/17584765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddm123
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