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Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
Changes in the composition of glycans added to glycoproteins and glycolipids are characteristic of the change to malignancy. Sialyl-Tn (STn) is expressed by 25–30% of breast carcinomas but its expression on normal tissue is highly restricted. Sialyl-Tn is an O-linked disaccharide that can be carried...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695689/ https://ncbi.nlm.nih.gov/pubmed/19436292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605083 |
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