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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Although plasmacytoid dendritic cells (pDCs) respond to virus replication in a non-specific fashion by producing large amounts of type I interferon, a rapid, direct role of pDCs in activating antiviral lymphocytes is less clear. Here we showed that pDCs possess the capacity to rapidly initiate antig...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695657/ https://ncbi.nlm.nih.gov/pubmed/18376401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1602 |
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