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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I

Although plasmacytoid dendritic cells (pDCs) respond to virus replication in a non-specific fashion by producing large amounts of type I interferon, a rapid, direct role of pDCs in activating antiviral lymphocytes is less clear. Here we showed that pDCs possess the capacity to rapidly initiate antig...

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Autors principals: Di Pucchio, Tiziana, Chatterjee, Bithi, Smed-Sörensen, Anna, Clayton, Sandra, Palazzo, Adam, Montes, Monica, Xue, Yaming, Mellman, Ira, Banchereau, Jacques, Connolly, John E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695657/
https://ncbi.nlm.nih.gov/pubmed/18376401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1602
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