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Engineering botulinum neurotoxin to extend therapeutic intervention
Clostridium botulinum neurotoxins (BoNTs) are effective therapeutics for a variety of neurological disorders, such as strabismus, blepharospam, hemificial spasm, and cervical dystonia, because of the toxin's tropism for neurons and specific cleavage of neuronal soluble N-ethylmaleimide-sensitiv...
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Autors principals: | , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
National Academy of Sciences
2009
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695098/ https://ncbi.nlm.nih.gov/pubmed/19487672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903111106 |
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