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NMR structures of three single-residue variants of the human prion protein

The NMR structures of three single-amino acid variants of the C-terminal domain of the human prion protein, hPrP(121–230), are presented. In hPrP(M166V) and hPrP(R220K) the substitution is with the corresponding residue in murine PrP, and in hPrP(S170N) it is with the corresponding Syrian hamster re...

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Autors principals: Calzolai, Luigi, Lysek, Dominikus A., Güntert, Peter, von Schroetter, Christine, Riek, Roland, Zahn, Ralph, Wüthrich, Kurt
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC26949/
https://ncbi.nlm.nih.gov/pubmed/10900000
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