Acetylation of Apurinic/Apyrimidinic Endonuclease-1 Regulates Helicobacter pylori-Mediated Gastric Epithelial Cell Apoptosis

BACKGROUND & AIMS: Helicobacter pylori-induced gastric epithelial cell (GEC) apoptosis is a complex process that includes activation of the tumor suppressor p53. p53-mediated apoptosis involves p53 activation, bax transcription and cytochrome c release from mitochondria. Apurinic/apyrimidinic en...

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Bibliographic Details
Main Authors: Bhattaracharyya, Asima, Chattopadhyay, Ranajoy, Burnette, Brent R., Cross, Janet V., Mitra, Sankar, Ernst, Peter B., Bhakat, Kishor K., Crowe, Sheila E.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694750/
https://ncbi.nlm.nih.gov/pubmed/19505426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.02.014
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