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The Neuronal Sortilin-Related Receptor Gene SORL1 and Late-Onset Alzheimer's Disease

Recent studies indicate that two clusters of single nucleotide polymorphisms in the neuronal sortilin-related receptor gene (SORL1) are causally associated with late-onset Alzheimer's disease (AD). At the cellular level, SORL1 is thought to be involved in intracellular trafficking of amyloid pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Joseph H., Barral, Sandra, Reitz, Christiane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694663/
https://ncbi.nlm.nih.gov/pubmed/18713574
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