Integrating siRNA and protein–protein interaction data to identify an expanded insulin signaling network

Insulin resistance is one of the dominant symptoms of type 2 diabetes (T2D). Although the molecular mechanisms leading to this resistance are largely unknown, experimental data support that the insulin signaling pathway is impaired in patients who are insulin resistant. To identify novel components/...

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Detalhes bibliográficos
Main Authors: Tu, Zhidong, Argmann, Carmen, Wong, Kenny K., Mitnaul, Lyndon J., Edwards, Stephen, Sach, Iliana C., Zhu, Jun, Schadt, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694478/
https://ncbi.nlm.nih.gov/pubmed/19261841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.087890.108
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