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High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues

A proportion of the genetic variants underlying complex phenotypes do so through their effects on gene expression, so an important challenge in complex trait analysis is to discover the genetic basis for the variation in transcript abundance. So far, the potential of mapping both quantitative trait...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Guo-Jen, Shifman, Sagiv, Valdar, William, Johannesson, Martina, Yalcin, Binnaz, Taylor, Martin S., Taylor, Jennifer M., Mott, Richard, Flint, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694476/
https://ncbi.nlm.nih.gov/pubmed/19376938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.088120.108
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