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Simulating the Collaborative Cross: Power of Quantitative Trait Loci Detection and Mapping Resolution in Large Sets of Recombinant Inbred Strains of Mice

It has been suggested that the collaborative cross, a large set of recombinant inbred strains derived from eight inbred mouse strains, would be a powerful resource for the dissection of complex phenotypes. Here we use simulation to investigate the power of the collaborative cross to detect and map s...

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Detalhes bibliográficos
Main Authors: Valdar, William, Flint, Jonathan, Mott, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456308/
https://ncbi.nlm.nih.gov/pubmed/16361245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039313
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